Detalhe da pesquisa
1.
Increased adipocyte O2 consumption triggers HIF-1α, causing inflammation and insulin resistance in obesity.
Cell
; 157(6): 1339-1352, 2014 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-24906151
2.
Leveraging model-based study designs and serial micro-sampling techniques to understand the oral pharmacokinetics of the potent LTB4 inhibitor, CP-105696, for mouse pharmacology studies.
Xenobiotica
; 47(7): 600-606, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-27435693
3.
LRP6 exerts non-canonical effects on Wnt signaling during neural tube closure.
Hum Mol Genet
; 22(21): 4267-81, 2013 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23773994
4.
Both microsatellite length and sequence context determine frameshift mutation rates in defective DNA mismatch repair.
Hum Mol Genet
; 19(13): 2638-47, 2010 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20418486
5.
Flanking nucleotide specificity for DNA mismatch repair-deficient frameshifts within activin receptor 2 (ACVR2).
Mutat Res
; 729(1-2): 73-80, 2012 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-22001236
6.
Microsatellite instability, EMAST, and morphology associations with T cell infiltration in colorectal neoplasia.
Dig Dis Sci
; 57(1): 72-8, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21773681
7.
Microsatellite alterations at selected tetranucleotide repeats are associated with morphologies of colorectal neoplasias.
Gastroenterology
; 139(5): 1519-25, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20708618
8.
TGF-beta downregulates PTEN via activation of NF-kappaB in pancreatic cancer cells.
Am J Physiol Gastrointest Liver Physiol
; 298(2): G275-82, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19940030
9.
The CLK inhibitor SM08502 induces anti-tumor activity and reduces Wnt pathway gene expression in gastrointestinal cancer models.
Cancer Lett
; 473: 186-197, 2020 03 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-31560935
10.
Chronic fractalkine administration improves glucose tolerance and pancreatic endocrine function.
J Clin Invest
; 128(4): 1458-1470, 2018 04 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29504946
11.
Time-restricted feeding improves insulin resistance and hepatic steatosis in a mouse model of postmenopausal obesity.
Metabolism
; 65(12): 1743-1754, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27832862
12.
LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes.
Nat Med
; 21(3): 239-247, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25706874
13.
Characterization of distinct subpopulations of hepatic macrophages in HFD/obese mice.
Diabetes
; 64(4): 1120-30, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25315009
14.
Adipocyte SIRT1 knockout promotes PPARγ activity, adipogenesis and insulin sensitivity in chronic-HFD and obesity.
Mol Metab
; 4(5): 378-91, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25973386
15.
Vitamin E supplementation reverses the age-associated decrease in effective immune synapse formation in CD4+ T cells.
Ann N Y Acad Sci
; 1031: 412-4, 2004 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-15753183
16.
Effect of age on susceptibility to azoxymethane-induced colonic aberrant crypt foci formation in C57BL/6JNIA mice.
J Gerontol A Biol Sci Med Sci
; 58(5): B400-5, 2003 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-12730247
17.
A Gpr120-selective agonist improves insulin resistance and chronic inflammation in obese mice.
Nat Med
; 20(8): 942-7, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24997608
18.
Oxidative stress induces nuclear-to-cytosol shift of hMSH3, a potential mechanism for EMAST in colorectal cancer cells.
PLoS One
; 7(11): e50616, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23226332
19.
Cyclin E and histone H3 levels are regulated by 5-fluorouracil in a DNA mismatch repair-dependent manner.
Cancer Biol Ther
; 10(11): 1147-56, 2010 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20930505
20.
Mesalazine reduces mutations in transforming growth factor beta receptor II and activin type II receptor by improvement of replication fidelity in mononucleotide repeats.
Clin Cancer Res
; 16(6): 1950-6, 2010 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20197483